Full map: http://goo.gl/maps/2viKb
Thanks to Berlino Explorer (http://www.berlino-explorer.com) for some suggestions.
You can start it from U-Görlitzer Bahnhof and have a look to the park, which I personally don't find really attractive, being one of the only park in Berlin without trees. But Görli (1) was a train station before, but after the war it has been demolished. From the park, passing through the Edelweiss restaurant with its famous terraces, you'll arrive in Lausitzer Platz (2), with Emmaus Church. The zone was a time famous for its punk scene, but gentrification and time has changed completaly this area. Leading a bit north you'll arrive at the Markhalle Neun (3), which is an indoor market opened on Friday and Saturday. From this area you can move to Marriannenplatz and the Künstlerhaus Bethanien (4), which was originally an hospital but it is now a art space - the entrance is really nice and you can go inside to have a look usually. Not far from here you'll surely see (5) Das Baumhaus an der Mauer (the Treehouse on the Wall), an house built by Osman Kalin - a turkish immigrant - on the no man's land during the division of the city.
By the river you'll find the Eisfabrik (6), an old ice factory which is abandoned, you can have a look from outside, but to go inside is dangerous and it's illegal.
Going back to the canal, you'll arrive at the canal besin Engelbeck of Luisenstädtischer Kanal (7), which were used for transportation and for design, but then partially filled and reused as gardens.
Out itinerary ends at SO36 (8), a music club focused on punk music in the 1970s, which was often frequented by musicians such as Iggy Pop and David Bowie.